Senescence‐associated β‐galactosidase reveals the abundance of senescent CD8+ T cells in aging humans

Abstract excerpt

Aging leads to a progressive functional decline of the immune system, rendering the elderly increasingly susceptible to disease and infection. The degree to which immune cell senescence contributes to this decline remains unclear, however, since markers that label immune cells with classical features of cellular senescence accurately and comprehensively have not been identified. Using a second-generation...

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