Article

Benign Meningiomas Develop Through a Four-Hit Mechanism

2024-11-08

Abstract excerpt

<title>Abstract</title> <p><bold>Purpose</bold>: Meningiomas are central nervous system tumors whose incidence increases with age. Benign meningioma pathogenesis involves germline or somatic mutation of target genes, such as <italic>NF2</italic>, leading to clonal expansion. We used an established cancer epidemiology model to investigate the number of rate-limiting steps sufficient for benign meningioma developme...

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Literature Corpus work: 97f0316b-d6f5-5c9d-b52f-f905a6d7ee8c
DOI: 10.21203/rs.3.rs-5253027/v1

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