Article
Diseases of epidermal keratins and their linker proteins.
Experimental cell research - 10 Jun 2007
Uitto Jouni, Richard Gabriele, McGrath John A
Abstract excerpt
Epidermal keratins, a diverse group of structural proteins, form intermediate filament networks responsible for the structural integrity of keratinocytes. The networks extend from the nucleus of the epidermal cells to the plasma membrane where the keratins attach to linker proteins which are part of desmosomal and hemidesmosomal attachment complexes. The expression of specific keratin genes is regulated by...
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