Article

Nesfatin-1 mitigates calcific aortic valve disease via suppressing ferroptosis mediated by GSH/GPX4 and ZIP8/SOD2 axes

2024-05-08

Abstract excerpt

<title>Abstract</title> <p><bold>Objective: </bold>Calcific aortic valve disease (CAVD) is a prevalent condition in the elderly population, lacking effective medical treatments. Nesfatin-1, a hypothalamic peptide generated from Nucleobindin 2 processing, has been implicated in both physiological and pathological calcification. In this study, we aimed to investigate the role of Nesfatin-1 in facilitating the trans...

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Literature Corpus work: 97cb7057-6bc2-560d-895f-b99ead29cff2
DOI: 10.21203/rs.3.rs-4345265/v1

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