Article

Pharmacologic Inhibition of Ferroptosis Attenuates Experimental Abdominal Aortic Aneurysm Formation

2024-06-22

Abstract excerpt

<h4>ABSTRACT</h4> The pathogenesis of abdominal aortic aneurysm (AAA) formation involves vascular inflammation, thrombosis formation and programmed cell death leading to aortic remodeling. Recent studies have suggested that ferroptosis, an excessive iron-mediated cell death, can regulate cardiovascular diseases, including AAAs. However, the role of ferroptosis in immune cells, like macrophages, and ferroptosis-re...

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Literature Corpus work: bc9bc380-f5ad-5cdd-a3d3-68fc9baf7a15
DOI: 10.1101/2024.06.18.599427

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