Article
The genetics of cannabis lifetime use.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Feb 2026
Bright Uri, Beck Sarah, Galimberti Marco, Gupta Priya, Chen Yu, Dao Cecilia, Nunez Yaira Z, Kranzler Henry R, Zhou Yu, Zhang Yingzhe, Choi Karmel W, Levey Daniel F, Gelernter Joel
Abstract excerpt
Cannabis is one of the most commonly used drugs in the world, and use is trending alarmingly higher. We aimed to examine the genetic basis of cannabis lifetime use (CanLU) and its genetic relationships with a variety of psychiatric- and physical health-related phenotypes. We conducted a multi-ancestral genome-wide association study (GWAS) of CanLU using data from All of Us in five genetic populations. We...
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