Article

SCF <sup>FBXW11</sup> complex targets interleukin-17 receptor A for ubiquitin-proteasome-mediated degradation

2023-06-22

Abstract excerpt

Interleukin-17 (IL-17) is a pro-inflammatory cytokine, participating in innate and adaptive immune responses, that plays an important role in host defense, autoimmune diseases, tissue regeneration, metabolic regulation, and tumor progression. Post-translational modifications (PTMs) are crucial for protein function, stability, cellular localization, cellular transduction, and cell death. However, PTMs of IL-17 rece...

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Literature Corpus work: 97b52e4e-e286-57ec-8cf9-65f40cbc1347
DOI: 10.1101/2023.06.21.545972

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