Article

ZNF500 suppresses the proliferation of breast cancer cells and sensitizes them to chemotherapy by stabilizing p53 in a manner that is competitive to MDM2

2023-03-21

Abstract excerpt

<h4>Background: </h4> Zinc finger protein 500 (ZNF500) has an unknown expression pattern and biological function in human tissues. This study was designed to determine what role ZNF500 played in breast cancer progression and chemotherapy resistance. <h4>Methods: </h4>: Firstly, we assessed the expression pattern of ZNF500 by bioinformatics assay and immunohistochemistry staining. Colony formation assay, MTT assay...

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Literature Corpus work: 7e65fae9-0c0b-5dc6-9fe8-53ed93025b9e
DOI: 10.21203/rs.3.rs-2694228/v1

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