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Article

HN1 contributes to migration, invasion, and tumorigenesis of breast cancer by enhancing MYC activity

11 May 2017

Abstract excerpt

BACKGROUND: Hematological and neurological expressed 1 (HN1) is upregulated in many tumors, but the role of HN1 in breast cancer progression and its regulatory mechanism have not been well understood. METHODS: To study the role of HN1 in the initiation and progression of breast cancer, we examined HN1 levels in breast cancer cells and tissues and analyzed the relationship between HN1 levels and patient survival....

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PMID: 28490334
DOI: 10.1186/s12943-017-0656-1

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