Article

LncRNA-mediated organization of oncogenic chromatin state is a targetable vulnerability in leukemia

2026-08-11

Abstract excerpt

Long non-coding RNAs (lncRNAs) are increasingly recognized as critical regulators of gene expression underlying various cellular functions, however, the functional and mechanistic contributions of most lncRNAs to tumorigenesis remain poorly defined, and targeting of lncRNAs is challenging with conventional therapeutic approaches. Here, we uncover human PAN3-AS1 and its murine ortholog Lnc35682, previously uncharac...

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Literature Corpus work: 97881910-2a62-5c35-9276-8093003e2ad7
DOI: 10.64898/2026.08.10.744058

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