Article
A Petri Net–Based Computational Framework for Oxygen-Sensitive Regulation of Pyruvate Metabolism in <i>Mycobacterium tuberculosis</i>
2025-09-06
Abstract excerpt
Pyruvate serves as a central hub of cellular metabolism, linking glycolysis with downstream pathways such as the tricarboxylic acid (TCA) cycle, gluconeogenesis, and fermentation. Its metabolic flexibility enables organisms to switch between oxidative and fermentative fates depending on oxygen availability and environmental stress. In this study, a Petri net (PN) model of pyruvate metabolism in Mycobacterium tube...
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Identifiers and source
- Literature Corpus work
- 977f7cba-46a1-5602-ba3b-c9159ea7fac3
- DOI
- 10.1101/2025.09.02.673648
