Bow-tie signaling in c-di-GMP: Machine learning in a simple biochemical network.

Abstract excerpt

Bacteria of many species rely on a simple molecule, the intracellular secondary messenger c-di-GMP (Bis-(3'-5')-cyclic dimeric guanosine monophosphate), to make a vital choice: whether to stay in one place and form a biofilm, or to leave it in search of better conditions. The c-di-GMP network has a bow-tie shaped architecture that integrates many signals from the outside world-the input stimuli-into intracellular...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Biofilms
• Share to Cell Movement