Article

Reconstruction of the cell entry pathway of an extinct virus

2018-05-25

Abstract excerpt

Endogenous retroviruses (ERVs), remnants of ancient germline infections, comprise 8% of the human genome. The most recently integrated includes human ERV-K (HERV-K) where several envelope ( env ) sequences remain intact. Viral pseudotypes decorated with one of those Envs are infectious. Using a recombinant vesicular stomatitis virus encoding HERV-K Env as its sole attachment and fusion protein (VSV-HERVK) we cond...

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Literature Corpus work: 9766396d-5764-5719-8565-3a32fbb8a460
DOI: 10.1101/331363

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