Article

Insights into the acquisition of the <i>pks</i> island and production of colibactin in the <i>Escherichia coli</i> population

2021-04-13

Abstract excerpt

<h4>ABSTRACT</h4> The pks island codes for the enzymes necessary for synthesis of the genotoxin colibactin, which contributes to the virulence of Escherichia coli strains and is suspected of promoting colorectal cancer. From a collection of 785 human and bovine E. coli isolates, we identified 109 strains carrying a highly conserved pks island, mostly from the phylogroup B2, but also from phylogroups A, B1 and...

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Literature Corpus work: 971dffad-1e61-528d-bb0f-d3fbf7dff42c
DOI: 10.1101/2021.04.13.439611

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