Article

Characterization of Pancreatic Cancer with Ultra-low Tumor Mutational Burden

2023-01-10

Abstract excerpt

In pancreatic cancer (PC), Tumor mutation burden (TMB) has been reported to be lower than in other cancers, with its clinical significance remaining unclear. We analyzed the dataset of whole-exome sequencing and gene expression profiling of 93 resected PC cases. The median TMB was 0.24. The TMB was classified as High (≥ 5.0), Low (< 5.0, ≥ 1.0), or Ultra-low (< 1.0). Nineteen samples (20%) were classified as TMB-l...

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Literature Corpus work: 970d7cce-3df4-555a-ab47-ef30be3f71ae
DOI: 10.21203/rs.3.rs-2449003/v1

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