Article
Mutational burden of resectable pancreatic cancer, as determined by whole transcriptome and whole exome sequencing, predicts a poor prognosis.
International journal of oncology - 1 Jun 2018
Grassi Elisa, Durante Sandra, Astolfi Annalisa, Tarantino Giuseppe, Indio Valentina, Freier Eva, Vecchiarelli Silvia, Ricci Claudio, Casadei Riccardo, Formica Francesca, Filippini Daria, Comito Francesca, Serra Carla, Santini Donatella, D' Errico Antonietta, Minni Francesco, Biasco Guido, Di Marco Mariacristina
Abstract excerpt
Despite the genomic characterization of pancreatic cancer (PC), marked advances in the development of prognosis classification and novel therapeutic strategies have yet to come. The present study aimed to better understand the genomic alterations associated with the invasive phenotype of PC, in order to improve patient selection for treatment options. A total of 30 PC samples were analysed by either whole...
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