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Article

Characterization of tumors with ultralow tumor mutational burden in Japanese cancer patients.

Cancer science - 1 Oct 2020

Hatakeyama Keiichi, Nagashima Takeshi, Ohshima Keiichi, Ohnami Sumiko, Ohnami Shumpei, Shimoda Yuji, Naruoka Akane, Maruyama Koji, Iizuka Akira, Ashizawa Tadashi, Mochizuki Tohru, Urakami Kenichi, Akiyama Yasuto, Yamaguchi Ken

Abstract excerpt

Tumor mutational burden analysis using whole-exome sequencing highlights features of tumors with various mutations or known driver alterations. Cancers with few changes in the exon regions have unclear characteristics, even though low-mutated tumors are often detected in pan-cancer analysis. In the present study, we analyzed tumors with low tumor mutational burden listed in the Japanese version of The Cancer...

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Identifiers

PMID: 32662546
DOI: 10.1111/cas.14572
PMCID: PMC7540986

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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