Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database.

Journal of gastroenterology - 1 Feb 2024

Sakakida Tomoki, Ishikawa Takeshi, Doi Toshifumi, Morita Ryuichi, Kataoka Seita, Miyake Hayato, Yamaguchi Kanji, Moriguchi Michihisa, Sogame Yoshio, Yasuda Hiroaki, Iwasaku Masahiro, Konishi Hideyuki, Takayama Koichi, Itoh Yoshito

Abstract excerpt

BACKGROUND: Microsatellite instability high (MSI-H) and tumor mutational burden high (TMB-high) pancreatic cancer are rare, and information is lacking. Based on the C-CAT database, we analyzed the clinical and genomic characteristics of patients with these subtypes. METHODS: We retrospectively reviewed data on 2206 patients with unresectable pancreatic adenocarcinoma enrolled in C-CAT between July 2019 and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenocarcinoma
Share to Biomarkers, Tumor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA Helicases

Share to Microsatellite Instability

Share to Mutation

Share to Nuclear Proteins

Share to Pancreatic Neoplasms

Share to Transcription Factors

Source

Identifiers

PMID: 38006445
DOI: 10.1007/s00535-023-02058-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genomic profile and clinical features of MSI-H and TMB-high pancreatic cancers: real-world data from C-CAT database.PMID 38006445Read ↗

Genetic and Clinical Characteristics of Patients With Tumor Mutation Burden-High Unresectable Pancreatic Cancer and the Efficacy of Pembrolizumab Treatment.Semantic proximity Read ↗

Tumor Mutational Burden in Real-World Patients With Pancreatic Cancer: Genomic Alterations and Predictive Value for Immune Checkpoint Inhibitor EffectivenessSemantic proximity Read ↗

Utility of Comprehensive Genomic Profiling Tests for Patients with Incurable Pancreatic Cancer in Clinical PracticeSemantic proximity Read ↗

Clinical Utility of Comprehensive Genomic Profiling for Advanced Pancreatic Cancer: Insights from Real-World Data AnalysisSemantic proximity Read ↗

NGS-based targeted gene mutational profiles in Korean patients with pancreatic cancerSemantic proximity Read ↗

Molecular and Clinical Features of Pancreatic Acinar Cell Carcinoma: A Single Institution Case SeriesSemantic proximity Read ↗

Factors associated with actionable gene aberrations in pancreatic cancer based on the C-CAT database.Semantic proximity Read ↗

Smaller panel, similar results: genomic profiling and molecularly informed therapy in pancreatic cancerSemantic proximity Read ↗

Hypermutation In Pancreatic Cancer.Semantic proximity Read ↗

Multi-omic characterization reveals a distinct molecular landscape in young-onset pancreatic cancerSemantic proximity Read ↗

Lynch Syndrome and Somatic Mismatch Repair Variants in Pancreas CancerSemantic proximity Read ↗

Precision Oncology in Pancreatic Cancer: Experiences and Challenges of the CCCMunichLMU Molecular Tumor Board.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.