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A Multi-Dataset Transcriptomic Analysis Unravels Core Mechanisms Involving Vitamin D Metabolism and Inflammatory Pathways for Frailty Diagnosis

2026-03-20

Abstract excerpt

Frailty is a prevalent geriatric syndrome, and the shortage of objective biomarkers restricts its early diagnosis and intervention. This study aimed to identify robust molecular signatures and diagnostic markers for frailty using bioinformatics analyses of multiple independent datasets. Two transcriptome datasets (GSE144304, n=80; GSE287726, n=70) were obtained from the GEO database. We performed differential gene...

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Literature Corpus work
96fe64ec-97e6-568f-ad18-a183a7a31c2b
DOI
10.64898/2026.03.18.712587
Open publication

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A Multi-Dataset Transcriptomic Analysis Unravels Core Mechanisms Involving Vitamin D Metabolism and Inflammatory Pathways for Frailty DiagnosisDOI 10.64898/2026.03.18.712587
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