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Article

Association of serum metabolites with frailty phenotype and its components: a cross-sectional case-control study.

Biogerontology - 6 Dec 2024

Shida Takashi, Hatanaka Sho, Kojima Narumi, Ohta Takahisa, Osuka Yosuke, Maruo Kazushi, Sasai Hiroyuki

Abstract excerpt

New insights into the metabolic mechanisms of frailty are needed. This study aimed to identify serum metabolites linked to frailty phenotype and its component through gas chromatography-mass spectrometry metabolomic analysis among community-dwelling older individuals. An exploratory, cross-sectional case-control study. Setting and participants: The participants were recruited from the ''Otassha Study,'' a cohort...

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PMID: 39643817
DOI: 10.1007/s10522-024-10166-y

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