Article

LMM-MQM time series mapping - An application in a murine advanced intercross line identifies novel growth QTLs

2022-01-25

Abstract excerpt

The Berlin Fat Mouse Inbred line 860 (BFMI860) is a mouse model for juvenile obesity. Previously, a recessive major effect locus ( jObes1 ) was identified on chromosome 3 explaining around 26% of the body weight variance in an BFMI860xC57BL/6NCrl advanced intercross line. The aim of this study was to discover additional QTL. Time series body weight data were modeled using linear mixed models (LMM), while a multi...

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Literature Corpus work: 96f05aed-8a9f-5834-8c6f-6901e388c0b7
DOI: 10.1101/2022.01.23.477441

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