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Article

A flexible estimating equations approach for mapping function-valued traits.

Genetics - 1 Sept 2011

Xiong Hao, Goulding Evan H, Carlson Elaine J, Tecott Laurence H, McCulloch Charles E, Sen Saunak

Abstract excerpt

In genetic studies, many interesting traits, including growth curves and skeletal shape, have temporal or spatial structure. They are better treated as curves or function-valued traits. Identification of genetic loci contributing to such traits is facilitated by specialized methods that explicitly address the function-valued nature of the data. Current methods for mapping function-valued traits are mostly...

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PMID: 21705752
DOI: 10.1534/genetics.111.129221
PMCID: PMC3176135

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