Article

MosaicLev: Modified Levenshtein distance for mobile element-aware genome comparison

2026-02-05

Abstract excerpt

<h4>Motivation</h4> Somatic genetic mosaicism arises when genomes diverge across cells during development, in part due to the activity of transposons (cut–paste) and retrotransposons (copy–paste). Standard sequence comparison methods are not motif-aware, penalizing mobile element insertions based on length rather than recognizing them as single biological events. <h4>Results</h4> We introduce a modified Levensht...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 96e0d817-4895-57a1-9de9-0c57dd3f2982
DOI: 10.64898/2026.02.03.703520

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

MosaicLev: Modified Levenshtein distance for mobile element-aware genome comparisonDOI 10.64898/2026.02.03.703520Read

A Unified Framework to Analyze Transposable Element Insertion Polymorphisms using Graph GenomesSemantic proximity Read

gmos: Rapid detection of genome mosaicism over short evolutionary distancesSemantic proximity Read

Interrogation of the integrated mobile genetic elements in gut-associated <i>Bacteroidaceae</i> with a consensus prediction approachSemantic proximity Read

TEvarSim: A genome simulator for transposable element (TE) variants.Semantic proximity Read

The Statistics of k-mers from a Sequence Undergoing a Simple Mutation Process Without Spurious Matches.Semantic proximity Read

The Mobile Element Locator Tool (MELT): population-scale mobile element discovery and biology.Semantic proximity Read

Systematic identification of cargo-mobilizing genetic elements reveals new dimensions of eukaryotic diversity.Semantic proximity Read

Identifying the essential genes of <i>Mycobacterium avium</i> subsp. <i>hominissuis</i> with Tn-Seq using a rank-based filter procedureSemantic proximity Read

Benchmarking computational tools for polymorphic transposable element detection.Semantic proximity Read

T-lex2: genotyping, frequency estimation and re-annotation of transposable elements using single or pooled next-generation sequencing dataSemantic proximity Read

Systematic comparative benchmarking of computational methods for the detection of transposable elements in long-read sequencing dataSemantic proximity Read

Gnom(Cmp): a quantitative approach for comparative analysis of closely related genomes of bacterial pathogens.Semantic proximity Read