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The Mobile Element Locator Tool (MELT): population-scale mobile element discovery and biology.

Genome research - 1 Nov 2017

Gardner Eugene J, Lam Vincent K, Harris Daniel N, Chuang Nelson T, Scott Emma C, Pittard W Stephen, Mills Ryan E, Devine Scott E

Abstract excerpt

Mobile element insertions (MEIs) represent ∼25% of all structural variants in human genomes. Moreover, when they disrupt genes, MEIs can influence human traits and diseases. Therefore, MEIs should be fully discovered along with other forms of genetic variation in whole genome sequencing (WGS) projects involving population genetics, human diseases, and clinical genomics. Here, we describe the Mobile Element...

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PMID: 28855259
DOI: 10.1101/gr.218032.116
PMCID: PMC5668948

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