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Investigating mitochondrial impairment as a mechanism of statin-induced muscle toxicity

2019-01-01

Abstract excerpt

Statins, also known as 3-hydroxy-3-methylglutaryl coenzyme A reductase (HMG-CoAR) inhibitors, are currently the pharmaceutical intervention strategy of choice for the primary and secondary prevention of atherosclerotic disorders that are related to hypercholesterolemia. In most recipients, statin therapy is effective and well tolerated, however the most significant barrier to cardiovascular disease (CVD) risk redu...

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Literature Corpus work
96a68ce9-fc58-58e7-ab84-e8473ec7b542
DOI
10.17638/03055069
Open publication

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Investigating mitochondrial impairment as a mechanism of statin-induced muscle toxicityDOI 10.17638/03055069
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