Article

Genetically encoded cell-death indicators (GEDI) to detect an early irreversible commitment to neurodegeneration

2019-08-14

Abstract excerpt

Cell death is a critical process that occurs normally in health and disease. However, its study is limited due to available technologies that only detect very late stages in the process or specific death mechanisms. Here, we report the development of a new fluorescent biosensor called genetically encoded death indicator (GEDI). GEDI specifically detects an intracellular Ca 2+ level that cells achieve early in the...

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Literature Corpus work: 85125a8b-73c7-5a83-b08a-64698518f623
DOI: 10.1101/726588

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