Article

Prioritisation of Structural Variant Calls in Cancer Genomes

2016-11-02

Abstract excerpt

Sensitivity of short read DNA-sequencing for gene fusion detection is improving, but is hampered by the significant amount of noise composed of uninteresting or false positive hits in the data. In this paper we describe a tiered prioritisation approach to extract high impact gene fusion events. Using cell line and patient DNA sequence data we improve the annotation and interpretation of structural variant calls to...

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Literature Corpus work: 9659160b-9243-579f-91df-4e0087cebe2c
DOI: 10.1101/084640

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