Article

Sex biased human thymic architecture guides T cell development through spatially defined niches

2023-04-16

Abstract excerpt

<h4>Summary</h4> Within the thymus, regulation of the cellular cross-talk directing T cell development is dependent on spatial interactions within specialized niches. To create a holistic, spatially defined map of tissue niches guiding postnatal T cell development we employed the multidimensional imaging platform CO-detection by indEXing (CODEX), as well as CITE-seq and ATAC-seq. We generated age-matched 4–5-mont...

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Literature Corpus work: cca71d04-27c4-5f18-9cbc-0ae70ebddb75
DOI: 10.1101/2023.04.13.536804

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