Article

Hemoglobin Interacts with Endothelial Nitric Oxide Synthase to Regulate Vasodilation in Human Resistance Arteries

2021-04-09

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> In small arteries, constriction of vascular smooth muscle triggers local release of nitric oxide from the adjacent endothelial cell. This feedback vasodilation is a homeostatic mechanism that opposes vasoconstriction. Here, we investigate the role of endothelial alpha globin as a regulator of directed nitric oxide signaling across the myoendothelial junction. <h4>Methods</h4>...

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Literature Corpus work: 961682f7-7b23-55e2-9449-dc9f80b2e40b
DOI: 10.1101/2021.04.06.21255004

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