Article

<i>CASCADES</i> , a novel <i>SOX2</i> super-enhancer associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma multiforme

2020-09-06

Abstract excerpt

<h4>ABSTRACT</h4> Glioblastoma multiforme (GBM) is the most common primary malignant brain tumor in adults, with a median survival of just over one year. The failure of available treatments to achieve remission in patients with GBM has been attributed to the presence of cancer stem cells (CSCs), which are thought to play a central role in tumor development and progression and serve as a treatment-resistant cell r...

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Literature Corpus work: 95498a2f-75d4-5870-8eb1-b175c357fe69
DOI: 10.1101/2020.09.05.284349

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