Article

Data-driven learning how oncogenic gene expression locally alters heterocellular networks

2020-05-05

Abstract excerpt

<h4>ABSTRACT</h4> Discovering and developing pharmaceutical drugs increasingly relies on mechanistic mathematical modeling and simulation. In immuno-oncology, models that capture causal relations among genetic drivers of oncogenesis, functional plasticity, and host immunity provide an important complement to wet experiments, given the cellular complexity and dynamics within tumors. Unfortunately, formulating such...

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Literature Corpus work: 950aed15-0f1f-539c-bb6e-f4b1b3c3e4d4
DOI: 10.1101/2020.05.04.077107

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