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Molecular hydrogen exerts neuroprotection against cerebral ischemia-reperfusion injury via Nrf2/HO-1-dependent ferroptosis inhibition in mice

2026-06-17

Abstract excerpt

<title>Abstract</title> <p> <bold>Background:</bold> Cerebral ischemia-reperfusion injury (CIRI) represents secondary brain damage induced by reperfusion after ischemic insult. Molecular hydrogen(H₂)is a highly permeable, biosafe and selective antioxidant, which has emerged as a promising redox-modulating agent in various oxidative stress-related disorders. Clinically, a balanced gas mixture composed of 67% (v/...

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Literature Corpus work
94fc96ca-1c33-5b75-b162-91a4ebe3d3b1
DOI
10.21203/rs.3.rs-9579320/v1
Open publication

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Molecular hydrogen exerts neuroprotection against cerebral ischemia-reperfusion injury via Nrf2/HO-1-dependent ferroptosis inhibition in miceDOI 10.21203/rs.3.rs-9579320/v1
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