Article

Astragaloside IV alleviates neuronal ferroptosis in ischemic stroke by regulating FTO-m6A-ACSL4 axis

2022-09-15

Abstract excerpt

<h4>Background: </h4> Ischemic stroke (IS) is a detrimental neurological disease with limited treatments options. Astragaloside IV (As-IV) was a promising bioactive constituent in the treatment of IS. However, the functional mechanism remains unclear. Methods IS cell and mice models were established by oxygen glucose deprivation /re-oxygenation (OGD/R) and middle cerebral artery occlusion (MCAO). RT-qPCR, Western...

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Literature Corpus work: 7b25ebf6-acd2-5aa1-a5d2-9514d60942e5
DOI: 10.21203/rs.3.rs-2047265/v1

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