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BACH1 encourages ferroptosis by activating KDM4C‐mediated COX2 demethylation after cerebral ischemia–reperfusion injury

11 May 2023

Abstract excerpt

It has been confirmed that BTB domain and CNC homologue 1 (BACH1) are involved in ferroptosis-related diseases. However, the function of BACH1 in cerebral ischemia-reperfusion injury (CIRI)-induced ferroptosis remains to be largely unrevealed. First, analysis of differentially expressed genes in CIRI based on the GEO dataset GSE119121 revealed that BACH1 was upregulated in CIRI. BACH1 level was prominently...

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PMID: 37161649
DOI: 10.1111/ejn.16035

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