Article

Generation of A New Therapeutic D-Peptide That Induces the Differentiation of Acute Myeloid Leukemia Cells Through A TLR-2 Signaling Pathway

2023-01-11

Abstract excerpt

<title>Abstract</title> Acute myeloid leukemia (AML) is caused by clonal disorders of hematopoietic stem cells. Differentiation therapy is emerging as an important treatment modality for leukemia, given its less toxicity and wider applicable population, but the arsenal of differentiation-inducing agents is still very limited. In this study, we adapted a competitive peptide phage display platform to search for...

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Literature Corpus work: 94f40108-3492-5ac2-831f-6f6b13539adc
DOI: 10.21203/rs.3.rs-2094714/v1

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