Article
Prussian Blue Nanozyme Potentiates Venetoclax Efficacy in Acute Myeloid Leukemia by Inducing a More Mature Phenotype.
International journal of nanomedicine - 1 Jan 2026
Yang Fan, Wu Hang, Yao Jing, Peng Xuelu, Yang Aiyun, Wen Tao, Meng Jie, Liu Jian, Zhang Yu, Wang Tao, Xu Haiyan
Abstract excerpt
Introduction: Acute Myeloid Leukemia (AML) is characterized by the clonal expansion of undifferentiated myeloid precursors and is associated with notably higher incidence and mortality rates in the elderly population. While the BCL-2 inhibitor Venetoclax has transformed the therapeutic landscape for patients with AML who were ineligible for intensive therapy, primary and acquired resistance remained major...
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