Article

Systems-level analysis identifies IRF6 as an inhibitor of epithelial-mesenchymal transition

2026-02-01

Abstract excerpt

<h4>Background</h4> Epithelial-mesenchymal transition (EMT) and its reverse process Mesenchymal-Epithelial Transition (MET) are crucial during metastasis and therapy resistance. While the dynamics and master regulators of EMT are well-studied, the transcription factors that can prevent EMT or promote MET are relatively less understood. <h4>Results</h4> Here, by integrating bulk and spatial transcriptomic data an...

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Literature Corpus work: 94f29174-74a2-5e9e-9854-27563dde00d3
DOI: 10.64898/2026.01.31.702311

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