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The ELF3 transcription factor is associated with an epithelial phenotype and represses epithelial-mesenchymal transition

2 Mar 2023

Abstract excerpt

BACKGROUND: Epithelial-mesenchymal plasticity (EMP) involves bidirectional transitions between epithelial, mesenchymal and multiple intermediary hybrid epithelial/mesenchymal phenotypes. While the process of epithelial-mesenchymal transition (EMT) and its associated transcription factors are well-characterised, the transcription factors that promote mesenchymal-epithelial transition (MET) and stabilise hybrid E/M...

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PMID: 36864480
DOI: 10.1186/s13036-023-00333-z

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