Article

Predicting Minimal Residual Disease in Acute Myeloid Leukemia through Stochastic Modeling of Clonality

2019-10-02

Abstract excerpt

Event-free and overall survival remains poor for acute myeloid leukemia (AML). Chemo-resistant clones contributing to relapse of the disease arise from minimal residual disease (MRD) rather than resulting from newly acquired mutations during or after chemotherapy. MRD is the presence of measurable leukemic cells using non-morphologic assays. It is considered a strong predictor of relapse. The dynamics of clones co...

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Literature Corpus work: 94d74d4c-2d1c-563e-b33a-58bb8c92b15e
DOI: 10.1101/790261

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