Article
Clonal relapse dynamics in acute myeloid leukemia following allogeneic hematopoietic cell transplantation.
Blood - 18 Jul 2024
Wienecke Clara Philine, Heida Bennet, Venturini Letizia, Gabdoulline Razif, Krüger Katja, Teich Katrin, Büttner Konstantin, Wichmann Martin, Puppe Wolfram, Neziri Blerina, Reuter Marlene, Dammann Elke, Stadler Michael, Ganser Arnold, Hambach Lothar, Thol Felicitas, Heuser Michael
Abstract excerpt
ABSTRACT: Patients with acute myeloid leukemia (AML) who experience relapse following allogeneic hematopoietic cell transplantation (alloHCT) face unfavorable outcomes regardless of the chosen relapse treatment. Early detection of relapse at the molecular level by measurable residual disease (MRD) assessment enables timely intervention, which may prevent hematological recurrence of the disease. It remains unclear...
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