Article

Integrative analysis of transcriptome and single-cell sequencing combined with experimental validation identifies biomarkers associated with T cell and senescence in sepsis

2026-01-09

Abstract excerpt

<title>Abstract</title> <p>Background Sepsis is an infection-induced systemic inflammatory response syndrome. T cell remodeling and senescence are linked to sepsis, so identifying T cell-related genes (TCRGs) and senescence-related genes (SRGs) as biomarkers is crucial for elucidating mechanisms, diagnosis, and targeted therapy. Methods TCRGs were derived from single-cell sequencing data. Biomarkers were screen...

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Literature Corpus work: 94d0ac83-b1fe-5def-95f2-090b1c0b851c
DOI: 10.21203/rs.3.rs-8343291/v1

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