Back to search

Article

Sphingolipid Metabolism-Related Genes as Diagnostic Markers in Pneumonia-Induced Sepsis: The AUG Model

2025-04-28

Abstract excerpt

<title>Abstract</title> <p>Pneumonia-induced sepsis (PIS) is a life-threatening condition with high mortality rates, necessitating the identification of biomarkers and therapeutic targets. Sphingolipid, particularly ceramides, are pivotal in modulating immune responses and determining cell fate. In this study, we identified a novel gene signature related to sphingolipid metabolism, comprising <italic>ACER3</itali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
8128074f-9807-5719-ad25-a2fb4adbd33a
DOI
10.21203/rs.3.rs-5857157/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Sphingolipid Metabolism-Related Genes as Diagnostic Markers in Pneumonia-Induced Sepsis: The AUG ModelDOI 10.21203/rs.3.rs-5857157/v1
Identification and Validation of a Lipid Metabolism-associated Gene Signature for Predicting Survival in Sepsis PatientsSemantic proximity
Characterization of lactylation-based phenotypes and molecular biomarkers in sepsis-associated acute respiratory distress syndromeSemantic proximity
A machine learning-based approach to prognostic model of sepsis with PANoptosis-related genes and performance of scRNA-seq data to assess prognostic signaturesSemantic proximity
Systematic characterization of pyroptosis-related gene patterns identifies potential prognostic inflammatory phenotypes in sepsis.Semantic proximity
Integrative analysis of transcriptome and single-cell sequencing combined with experimental validation identifies biomarkers associated with T cell and senescence in sepsisSemantic proximity
Predicting the prognosis in patients with sepsis by a pyroptosis-related gene signatureSemantic proximity
Identification of Immune-Related Key Genes as Potential Diagnostic Biomarkers of Sepsis in ChildrenSemantic proximity
The Optimization and Biological Significance of a 29-Host-Immune-mRNA Panel for the Diagnosis of Acute Infections and SepsisSemantic proximity
Identification and validation of m6A RNA methylation and ferroptosis-related biomarkers in sepsis: transcriptome combined with single-cell RNA sequencingSemantic proximity
Differential Transcriptomic Profiling Between Patients With Sepsis-Induced Ards And Sepsis Without Ards&nbsp;Semantic proximity
Gene expression profiling of mononuclear cells from patients with sepsis secondary to community-acquired pneumoniaSemantic proximity
Pyroptosis-related gene signature in neutrophils for predicting the prognosis of sepsisSemantic proximity
Select a neighboring publication to make it the new centre.