Article

Integrated Bioinformatics Analysis Identifies and Validates Novel Cellular Senescence-Associated Genes in Sepsis and Sepsis-Induced ARDS

2026-03-31

Abstract excerpt

Sepsis can lead to acute respiratory distress syndrome (ARDS) and is associated with a high mortality rate. This study investigated cellular senescence-related genes in sepsis and sepsis-induced ARDS to identify novel biomarkers. Using bioinformatics analyses including WGCNA and machine learning on public datasets, six hub genes (NFIL3, GARS, PIGM, DHRS4L2, CLIP4, LY86) were identified. These genes showed strong d...

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Literature Corpus work: e5a631e6-c1d8-5516-8c94-13bacc4e29d6
DOI: 10.64898/2026.03.30.26349474

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