Article
miR-200a-3p regulates PRKACB and participates in aluminium-induced tau phosphorylation in PC12 cells
2022-10-13
Abstract excerpt
Aluminium (Al) is an environmental neurotoxin that humans are widely exposed to, but the molecular mechanism of its toxic effects is not fully understood. Many studies have shown that exposure to Al can cause abnormal phosphorylation of the tau protein that is believed as one of pathological features of Alzheimer’s disease. Increasing evidence indicates that microRNAs (miRNAs) may be involved in the pathological p...
Topics
Open a Topic to create a Post that cites this publication.
- Aluminum toxicity and tolerance in plants and animals
- Alzheimer's disease research and treatments
- Amyotrophic Lateral Sclerosis Research
- Cholinesterase and Neurodegenerative Diseases
- MicroRNA in disease regulation
- Peptidase Inhibition and Analysis
- Phosphodiesterase function and regulation
- Protein Kinase Regulation and GTPase Signaling
Identifiers and source
- Literature Corpus work
- 94bf3acd-cd57-50f8-9575-b129a166b89c
- DOI
- 10.21203/rs.3.rs-2114796/v1
