Article

Genes associated with neuropsychiatric disease increase vulnerability to abnormal deep grey matter development

2018-06-12

Abstract excerpt

1. <h4>Background</h4> Neuropsychiatric disease has polygenic determinants but is often precipitated by environmental pressures, including adverse perinatal events. However, the way in which genetic vulnerability and early-life adversity interact remains obscure. Preterm birth is associated with abnormal brain development and psychiatric disease. We hypothesised that the extreme environmental stress of premature...

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Literature Corpus work: 943ff7b8-25fe-5c18-9f76-4639e23b0bd8
DOI: 10.1101/342394

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