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The metabolic, virulence and antimicrobial resistance profiles of colonizing <i>Streptococcus pneumoniae</i> shift after pneumococcal vaccine introduction in urban Malawi

2021-07-22

Abstract excerpt

Streptococcus pneumoniae accounts for at least 300,000 deaths from pneumonia, septicaemia and meningitis among children under 5-years-old worldwide. Protein–polysaccharide conjugate vaccines (PCVs) are highly effective at reducing vaccine serotype disease but emergence of non-vaccine serotypes and persistent nasopharyngeal carriage threaten to undermine this success. Here, we address the hypothesis that following...

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Literature Corpus work
084276a6-be4f-5169-8a4a-060717aadb97
DOI
10.1101/2021.07.21.21260914
Open publication

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The metabolic, virulence and antimicrobial resistance profiles of colonizing <i>Streptococcus pneumoniae</i> shift after pneumococcal vaccine introduction in urban MalawiDOI 10.1101/2021.07.21.21260914
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