Back to search

Article

Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of<i>Klebsiella pneumoniae</i>and stresses the importance to include temporal patterns for vaccine design considerations

2023-09-27

Abstract excerpt

Infections caused by multidrug-resistant gram-negative bacteria present a severe threat to global public health. The WHO defines drug-resistant Klebsiella pneumoniae as a priority pathogen for which alternative treatments are needed given the limited treatment options and the rapid acquisition of novel resistance mechanisms by this species. Longitudinal descriptions of genomic epidemiology of Klebsiella pneumoniae...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
82520c40-7d33-5b03-9a77-6b0b1934ae39
DOI
10.1101/2023.09.26.23296137
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of<i>Klebsiella pneumoniae</i>and stresses the importance to include temporal patterns for vaccine design considerationsDOI 10.1101/2023.09.26.23296137
Longitudinal analysis within one hospital in sub-Saharan Africa over 20 years reveals repeated replacements of dominant clones of Klebsiella pneumoniae and stresses the importance to include temporal patterns for vaccine design considerationsSemantic proximity
Genomic and antigenic diversity of carried <i>Klebsiella pneumoniae</i> isolates mirrors that of invasive isolates in Blantyre, MalawiSemantic proximity
Genomic and antigenic diversity of colonizing Klebsiella pneumoniae isolates mirrors that of invasive isolates in Blantyre, MalawiSemantic proximity
High ward-level and within-sample diversity of <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit revealed by single colony whole genome sequencing and post-enrichment metagenomicsSemantic proximity
Genomic characterization of<i>Klebsiella pneumoniae</i>causing invasive disease in South African infants: observational studies between 2018 to 2023Semantic proximity
Genomic analysis of extended-spectrum beta-lactamase (ESBL) producing <i>Escherichia coli</i> colonising adults in Blantyre, Malawi reveals previously undescribed diversitySemantic proximity
Antimicrobial resistance and virulence characteristics of <i>Klebsiella pneumoniae</i> isolates in KenyaSemantic proximity
Extended-Spectrum Beta-Lactamase <i>Klebsiella pneumoniae</i> on a Malawian neonatal unit is amplified by neonates and transmitted by maternal hands, cots and ward surfacesSemantic proximity
Molecular characterisation of a <i>Klebsiella pneumoniae</i> neonatal sepsis outbreak in a rural Gambian hospital: a retrospective genomic epidemiology investigationSemantic proximity
Genomic dissection of the bacterial population underlying<i>Klebsiella pneumoniae</i>infections in hospital patients: insights into an opportunistic pathogenSemantic proximity
High diversity of<i>Escherichia coli</i>causing invasive disease in neonates in Malawi poses challenges for O-antigen based vaccine approachSemantic proximity
A natural history of AMR in <i>Klebsiella pneumoniae</i> : Global diversity, predictors, and predictions of evolutionary pathwaysSemantic proximity
Select a neighboring publication to make it the new centre.