Article

Spatial transcriptomic characterization of COVID-19 pneumonitis identifies immune circuits related to tissue injury

2021-06-21

Abstract excerpt

Severe lung damage in COVID-19 involves complex interactions between diverse populations of immune and stromal cells. In this study, we used a spatial transcriptomics approach to delineate the cells, pathways and genes present across the spectrum of histopathological damage in COVID-19 lung tissue. We applied correlation network-based approaches to deconvolve gene expression data from areas of interest within well...

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Literature Corpus work: 93f21b8a-6153-5f63-aaf7-74e511c72ca1
DOI: 10.1101/2021.06.21.449178

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