Article

Genetic liability to sedentary behavior increases the risk of cardiovascular disease incidence: Evidence from the FinnGen cohort with 293,250 individuals

2024-06-20

Abstract excerpt

<h4>Background</h4> It is unclear how the genetics of sedentary behavior are associated with incident cardiovascular disease (CVD). We investigated the associations between genetic liability to sedentary behavior, sedentariness, and four main CVD outcomes: any CVD, hypertensive diseases, ischemic heart diseases, and cerebrovascular diseases. <h4>Methods</h4> Leisure screen time was used as a proxy for sedentary be...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 93eb655f-0165-5438-b336-ec28a33bae98
DOI: 10.1101/2024.06.20.24309213

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic liability to sedentary behavior increases the risk of cardiovascular disease incidence: Evidence from the FinnGen cohort with 293,250 individualsDOI 10.1101/2024.06.20.24309213Read

The effect of sedentary behaviour and physical activity on 1719 diseases: a Mendelian randomisation phenome-wide association study (MR-PheWAS)Semantic proximity Read

Genetic liability for cardiovascular disease, physical activity, and mortality – findings from The Finnish Twin CohortSemantic proximity Read

Genetic Liability to Higher Muscle Strength Associates with a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Physical Activity in Adulthood: A Longitudinal Cohort StudySemantic proximity Read

Exploring the causal relationship between sedentary behavior and cardiovascular disease: A two-sample Mendelian randomization analysis.Semantic proximity Read

Genetic susceptibility, screen-based sedentary activities and incidence of coronary heart disease.Semantic proximity Read

Sedentary Behavior, Physical Activity, and Hypertension: Genetic Liability and the Role of Metabolic Factors.Semantic proximity Read

Unhealthy Lifestyle, Genetics and Risk of Cardiovascular Disease and Mortality in 76,958 Individuals from the UK Biobank Cohort Study.Semantic proximity Read

Genome-wide association studies and Mendelian randomization analyses for leisure sedentary behavioursSemantic proximity Read

Evaluation of Genetics in the Association Between Cardiorespiratory Fitness and Health: Insights from a Genome-Wide Polygenic Score for Cardiorespiratory Fitness in the FinnGen and HUNT cohorts.Semantic proximity Read

Genetic variants related to physical activity or sedentary behaviour: a systematic review.Semantic proximity Read

Genetic Liability to Higher Muscle Strength Associates With a Lower Risk of Cardiovascular Disease Mortality in Men Irrespective of Leisure-Time Physical Activity in Adulthood: A Longitudinal Cohort Study.Semantic proximity Read

Physical activity, genetic predisposition, and incident cardiovascular disease: Prospective analyses of the UK BiobankSemantic proximity Read