Sedentary Behavior, Physical Activity, and Hypertension: Genetic Liability and the Role of Metabolic Factors.

Abstract excerpt

BACKGROUND: Whether sedentary behavior and physical activity causally influence hypertension remains uncertain. We used Mendelian randomization (MR) to examine whether genetically predicted domain-specific sedentary behaviors and leisure-time physical activity are associated with hypertension risk and to explore potential cardiometabolic pathways. METHODS: We performed a two-sample MR using genome-wide...

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